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. Author manuscript; available in PMC: 2024 Apr 19.
Published in final edited form as: Stem Cell Res. 2013 Mar 26;11(1):552–562. doi: 10.1016/j.scr.2013.03.001

Table 1. The various levels of cellular developmental potential.

Totipotency Potential to give rise to a functional organism with all its cell lineages. In mammals exclusively the zygote and the first four to eight blastomeres are totipotent.
Pluripotency Potential to give rise to all somatic lineages of the body; e.g. embryonic stem cells and induced pluripotent stem cells.
Multipotency Ability of adult stem cells to form multiple cell types of one lineage; e.g. hematopoietic stem cells.
Unipotency Cells form one cell type; e.g. spermatogonial stem cells, which at least under natural conditions, are only able to generate sperms.