Skip to main content
. Author manuscript; available in PMC: 2024 Apr 19.
Published in final edited form as: Stem Cell Res. 2013 Mar 26;11(1):552–562. doi: 10.1016/j.scr.2013.03.001

Table 2. Alternative methods for testing the pluripotency of stem cells.

System Assays
ES cell culture Molecular profiling by genomics, epigenomics, proteogenomics and glycomics.
Embryoid bodies Differentiation models assaying spontaneous differentiation, directed differentiation, and special assays such as vascularization or wound healing.
In silico models Computer based models and genome wide data sets obtained from microarrays and next-generation sequencing.
Alternative in vivo models Chicken egg model.
Organotypic models In situ analysis such as skin models, “stripped organ” models, and re-aggregation/integration assays.