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. Author manuscript; available in PMC: 2024 May 27.
Published in final edited form as: J Leukoc Biol. 2022 Feb 16;112(3):395–409. doi: 10.1002/JLB.1A0321-132RR

Figure 4. Neutrophil Phenotype.

Figure 4

CD11b (A) and ICAM-1 (B) expression levels among neutrophils from bone marrow, blood and peritoneal cavity at day 7 and day 10 after mock or microsphere-implantation procedure. Cells were either treated (stimulated) or not treated (unstimulated) with cytochalasin B (5 µg/ml) and fMLP (5 µM) ex-vivo, and expression levels of CD11b and ICAM-1 among neutrophils (Ly6G+ cells) was quantified. Saline and chitosan groups are representative of 2 independent experiments with total n = 4. Alginate group is representative of 1 independent experiment with n = 4 mice at each time point, involving both male and female mice (no difference was observed based on sex of mice). For statistical analyses, a one-way ANOVA was performed followed by Tukey post-test, and * = p < 0.05; ** = p < 0.01; *** = p < 0.001; and **** = p < 0.0001. Black – Mock, Orange – Chitosan, Green - Alginate