. Author manuscript; available in PMC: 2024 May 27.

Published in final edited form as: J Leukoc Biol. 2022 Feb 16;112(3):395–409. doi: 10.1002/JLB.1A0321-132RR

Table 2. Mathematical model based calculation of maturation time in bone marrow, and half-life in circulation and site of inflammation.

		Saline			Chitosan			Alginate
		Median	Range (central 95%)		Median	Range (central 95%)		Median	Range (central 95%)
Maturation time in bone marrow (h/s) (hours)	iABC	53.62	50.86	55.98	24.12	22.97	25.27	46.76	44.19	49.35
Maturation time in bone marrow (h/s) (hours)	GA	54.42	49.99	59.80	24.37	21.83	27.39	47.69	43.36	56.17
Half-life in blood (ln(2)/U) (hours)	iABC	4.69	4.33	5.36	2.79	2.52	3.33	6.43	5.90	7.46
Half-life in blood (ln(2)/U) (hours)	GA	1.8	0.43	5.35	1.8	0.44	4.72	2.5	0.42	8.05
Half-life in peritoneum (ln(2)/w) (hours)	iABC	3.09	1.95	4.74	6.69	4.45	8.44	0.46	0.35	1.09
Half-life in peritoneum (ln(2)/w) (hours)	GA	4.6	1.74	5.92	7.19	1.14	8.83	0.59	0.34	1.97