REAGENT or RESOURCE	SOURCE	IDENTIFIER
Antibodies
Rabbit anti-DOZI	This manuscript	N/A
chicken anti-GFP	Abcam	Cat#ab13970
goat anti-rabbit Alexafluor 594	ThermoFisher	A-11012
goat anti-chicken Alexafluor 488	ThermoFisher	A-11035
Critical commercial assays
10x Genomics Chromium 3’ v2	10X Genomics	PN-120237
BD Influx cell sorter	BD	N/A
Deposited data
Single-cell RNA-seq data	This manuscript	ENA: PRJEB44892
Bulk RNA-seq data	This manuscript	GEO: GSE110201, GSE168817
Code	This manuscript	https://doi.org/10.5281/zenodo.7317469
mass spectrometry proteomics data	This manuscript	PRIDE: PXD033827
Experimental models: Organisms/strains
P. berghei: 820cl1m1cl1 line parasites	Mair et al.20 and Ponzi et al.45	820cl1m1cl1
P. berghei: PBGAMi line parasites	Kent et al.6	PBGAMi
Rat: RCC Han Wistar outbred (female)	Envigo	RccHan:WIST
Mouse: BALB/c inbred (female)	Wellcome Sanger Institute & Envigo & Charles River Europe	BALB/cOlaHsd
Mouse: SCID (female)	Envigo	C.B-17/IcrHan®Hsd-Prkdcscid
Mouse: outbred TO (female)	Envigo	HsdOla:TO
Mouse: C57BL/6N (female)	Envigo	C57BL/6N
Oligonucleotides
PCR primers used in this study	This manuscript	itemized in Table S1
Recombinant DNA
Gene targeting vectors used in this study	https://plasmogem.umu.se/pbgem/	Itemized in Table S1
Software and algorithms
Rstudio (v4.0.3)	https://www.rstudio.com/	N/A
GraphPad Prism 9	http://www.graphpad.com/scientific-software/	N/A
R (v4.0.3)	https://www.r-project.org/	N/A
Flowjo (v7.6.5 and 10.6.1)	https://www.flowjo.com/solutions/flowjo	N/A
Samtools (v.2)		N/A
HISAT2 (v2.1.0)	Kim et al.46	N/A
HT-seq (v1.3.1 and v0.11.2)	Anders et al.47	N/A
DESeq2 (v1.18)	Love et al.48	N/A
Cell Ranger (v2.1.1)	10X Genomics	N/A
Seurat (v3.2.2)	Stuart et al.49	N/A
Mixtools (v1.2.0)	Benaglia et al.50	N/A
Monocle 3 (v0.2.3.0)	Cao et al.,51 Qiu et al.,52 and Trapnell et al.53	N/A
UMAP	McInnes et al.54	N/A
Discoverer v. 2.4	Thermo Fisher	N/A
SAINTexpress	Teo et al.55	N/A