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. Author manuscript; available in PMC: 2024 Jun 12.
Published in final edited form as: Cell Rep. 2024 Apr 4;43(4):114080. doi: 10.1016/j.celrep.2024.114080

Figure 6. Distinct reward-related signaling in different striatal regions.

Figure 6

(A) Mean PSTH of the change in GCaMP6f fluorescence (ΔF/F) in dopaminergic axons in DMS (yellow), DLS (blue), VLS (green), and NAc core (red) recorded with fiber photometry. (B) Mean peak change in fluorescence at reward in each striatal region. DLS and VLS exhibited distinct signals at reward compared to each other population; there was no significant difference between signals in DMS and NAc (P>0.05 one way ANOVA with Tukey’s post-hoc test; **** p < 0.0001). (C) Representative image showing the expression of GCaMP6f and the track (dashed line) of the optic fiber targeted to NAc core. N = 4 recording sessions in 4 mice, (1 recording session per region, per mouse).