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. 2024 Apr 16;162(1-2):53–64. doi: 10.1007/s00418-024-02280-2

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© The Author(s) 2024

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Fig. 2 — Detection of oncogenes on ecDNA by DNA-FISH. Left: DAPI stained metaphase spreads from a recurrent glioblastoma cell line E37. Right: DNA-FISH with a probe (red) detecting c-MYC. Arrows indicate examples of DNA-FISH signal on ecDNA for orientation. Scale bar: 10 µm