Table 3. Maximum toxicity grade reported on Radiation Therapy Oncology Group scales.
| No ADT group (n=737) | Short-course ADT group (n=743) | p value | ||||||
|---|---|---|---|---|---|---|---|---|
| Grade 1–2 | Grade 3 | Grade 4 | Grade 1–2 | Grade 3 | Grade 4 | |||
| Any toxicity | 407 (55%) | 114 (15%) | 7 (1%) | 442 (59%) | 90 (12%) | 10 (1%) | 0·17 | |
| Diarrhoea | 307 (42%) | 12 (2%) | 1 (<1%) | 322 (43%) | 13 (2%) | 0 | 0·67 | |
| Proctitis | 200 (27%) | 23 (3%) | 0 | 248 (33%) | 20 (3%) | 0 | 0·028 | |
| Cystitis | 199 (27%) | 15 (2%) | 2 (<1%) | 214 (29%) | 17 (2%) | 2 (<1%) | 0·84 | |
| Haematuria | 141 (19%) | 51 (7%) | 2 (<1%) | 155 (21%) | 28 (4%) | 2 (<1%) | 0·058 | |
| Urethral stricture | 74 (10%) | 49 (7%) | 3 (<1%) | 74 (10%) | 51 (7%) | 7 (1%) | 0·65 | |
Data are presented as n (%). Data were missing for six participants in the no ADT group and nine participants in the short-course ADT group. No grade 5 events were recorded. ADT=androgen deprivation therapy.