Table 3. Suggestions on when to adjudicate in future stroke trials.
Outcome | SI blind to treatment allocation when assessing outcome | SI not blind to treatment allocation when assessing outcome |
---|---|---|
Primary outcome: stroke or a composite including stroke | Adjudication is less important | Adjudication is more important |
Primary outcome: functional outcome measured on the mRS | Adjudication is less important | Adjudication is more important |
Subjective key safety or secondary outcome | Adjudication is less important | Adjudication is more important |
Objective key safety or secondary outcome | Adjudication is not important | Adjudication is more important |
Other outcome | Adjudication is not important | Adjudication is not important |
SI: site investigator; mRS: modified Rankin Scale.