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. Author manuscript; available in PMC: 2024 Sep 10.
Published in final edited form as: Int J Stroke. 2022 May 10;18(2):154–162. doi: 10.1177/17474930221094682

Table 3. Suggestions on when to adjudicate in future stroke trials.

Outcome SI blind to treatment allocation when assessing outcome SI not blind to treatment allocation when assessing outcome
Primary outcome: stroke or a composite including stroke Adjudication is less important Adjudication is more important
Primary outcome: functional outcome measured on the mRS Adjudication is less important Adjudication is more important
Subjective key safety or secondary outcome Adjudication is less important Adjudication is more important
Objective key safety or secondary outcome Adjudication is not important Adjudication is more important
Other outcome Adjudication is not important Adjudication is not important

SI: site investigator; mRS: modified Rankin Scale.