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| |||
|---|---|---|---|
| Entry | Cmpd. | R1 | IC50, nM PfSUB1 inhibition |
| 1 | 2a |
|
2.1±0.1 |
| 2 | 2b |
|
2.8±0.1 |
| 3 | 2c |
|
7.5±0.8 |
| 4 | 2d |
|
6.7±0.3 |
| 5 | 2e |
|
43.5±2.7 |
| 6 | 2f |
|
5.4±0.1 |
| 7 | 2g |
|
7.8±0.1 |
| 8 | 2h |
|
6.9±2.6 |
