Table 5. Cross-sectional associations between key determinants of inflammation and inflammatory biomarkers in the mothers cohort at mean age 47.57y.

Variable	Model 1			Model 2			Model 3
	Beta (se)	95% CI	p	Beta (se)	95% CI	p	Beta (se)	95% CI	p
GlycA
BMI  (kg/m2)	0.10 (0.002)	0.09, 0.10	<0.001	0.10 (0.002)	0.09, 0.10	<0.001	0.09 (0.003)	0.09, 0.10	<0.001
Age (months)	0.004 (0.003)	-0.002, 0.01	0.176	-	-	-	0.02 (0.003)	0.02, 0.03	<0.001
SEP (below degree level)	0.19 (0.02)	0.15, 0.22	<0.001	0.21 (0.02)	0.18, 0.24	<0.001	0.13 (0.02)	0.10, 0.16	<0.001
Grandparents Social Class (manual)	0.23 (0.04)	0.16, 0.30	<0.001	0.24 (0.04)	0.17, 0.31	<0.001	0.08 (0.03)	0.02, 0.15	0.013
Atopic diagnosis	0.04 (0.02)	-0.01, 0.08	0.133	0.04 (0.02)	-0.01, 0.09	0.115	0.02 (0.02)	-0.03, 0.06	0.474
CRP
BMI (kg/m2)	0.10 (0.002)	0.10, 0.11	<0.001	0.10 (0.002)	0.10, 0.11	<0.001	0.10 (0.003)	0.10, 0.11	<0.001
Age (months)	-0.004 (0.003)	-0.01, 0.002	0.278		-	-	0.01 (0.003)	0.002, 0.02	0.013
SEP below degree level)	0.15 (0.02)	0.12, 0.18	<0.001	0.16 (0.02)	0.12, 0.19	<0.001	0.07 (0.02)	0.04, 0.10	<0.001
Grandparents Social Class (manual)	0.18 (0.04)	0.11, 0.25	<0.001	0.18 (0.04)	0.11, 0.25	<0.001	0.05 (0.03)	-0.01, 0.12	0.097
Atopic diagnosis	0.04 (0.02)	-0.01, 0.09	0.155	0.04 (0.02)	-0.01, 0.09	0.137	0.01 (0.02)	-0.04, 0.05	0.738

^*Adjusted age, estimates for age were left as in Model 1

^**Adjusted for age, SEP, grandparents household social class and atopy. The variable was not included as a covariate if used as the exposure.