Fig. 3.
Comparison of antibody responses induced by Ad-F3–3 vaccines and OMV vaccine. BALB/c mice received 109 IU of full length Ad-F3–3 (N = 7), Ad-FliC-VR3–3 (N = 8) or 5 μg of OMV (44/76-FetAon PorAoff, N = 8). Individual antibody responses against recombinant rF3–3 (A) or against 44/76-FetAonPorAoff whole cells (B, pooled sera from each group) 6 weeks post vaccination are shown. Groups of 7 or 8 mice were used for the experiments as indicated above. Kruskal-Wallis test with Dunn’s multiple comparison was used to perform comparisons between the groups ∗ P ≤ 0.05 and ∗∗∗ P ≤ 0.001.
