Table 2.
Serum bactericidal responses in mice after immunisation with Ad-P1.7,16 or OMVs. SBA titres at two (week 2) and 6 weeks (week 14) post prime and boost immunisations respectively for Ad-P1.7,16 and OMV (44/76 FetAonPorAon ) SBA titres measured against target strain 44/76-SL performed using human complement and pooled mouse serum (N = 5, as described in Fig. 4A). ‘-’ indicates no boost.
| Prime | Boost | ||
|---|---|---|---|
| Prime vaccine | hSBA titre Week 2 | Boost vaccine | hSBA titre Week 14 |
| Ad-P1.7,16 | 1:4 | OMV | 1:128 |
| OMV | 1:64 | OMV | 1:1024 |
| Ad-P1.7,16 | 1:4 | - | < 1:4 |
| Naive | 1:4 | - | < 1:4 |