Table 3.
Serum bactericidal responses in mice after immunisation with Ad-F3–3, Ad-FliC-VR3–3 or OMVs. rSBA titres 6 weeks after prime and 6 weeks after boost (week 14) for Ad-F3–3, Ad-FliC-VR3–3 and OMV (44/76 FetAonPorAoff). SBA titres measured against target strain 44/76-SL performed using pooled mouse sera (N = 8, as described in Fig. 4B). ‘-’ indicates no boost.
| F3–3 Vaccines | |||
|---|---|---|---|
| Prime vaccine | Week 6 rSBA | Boost vaccine | Week 14 rSBA |
| Naive | <1:4 | – | – |
| Ad-F3–3 | <1:4 | OMV-44/76 FetAonPorAoff | <1:4 |
| Ad-FliC-VR3–3 | <1:4 | OMV-44/76 FetAonPorAoff | <1:4 |
| OMV-44/76 FetAonPorAoff | <1:4 | OMV-44/76 FetAonPorAoff | 1:32 |