Table 3.
In participants who made as per protocol visits, Geometric mean fold rise(95% CI) and seroconversion of IgG and IgA in 9-month and 12-month groups.
| 9-month | 12-month | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Visit 1–2 | Visit 1–3 | Visit 3–4 | Visit 1–4 | Visit 1–2 | Visit 1–3 | Visit 3–4 | Visit 1–4 | ||
| IgG | |||||||||
| Geometric mean fold rise (95 % CI) | 1087.12 (616.49–1557.75) |
87.90 (64.19–111.61) |
10.03 (5.99–14.07) |
684.72 (420.19to 949.24) |
713.43 (544.21–882.65) |
309.10 (186.41 to 431.79) |
1.15 (0.73–1.57) |
309.10 (186.41–431.79) |
|
| 4-fold increase (%) | 27/27 (100 %) | 32/32 (100 %) | 16/20 (80 %) | 20/20 (100 %) | 32/32 (100 %) | 16/16 (100 %) | 0/8 (0 %) | 10/10 (100 %) | |
| IgA | |||||||||
| Geometric mean fold rise (95 % CI) | 51.57 (18.02 85.13) |
9.59 (5.52–13.66) |
4.26 (2.77–5.75) |
21.41 (13.47–29.34) |
100.61 (–26.20–227.43) |
22.36 (11.46–33.26) |
0.97 (0.65 to1.29) |
22.83 (8.04–37.62) |
|
| 4-fold increase (%) |
27/27 (100 %) | 24/32 (75 %) | 9/20 (45 %) | 20/20 (100 %) | 31/32 (96.88 %) | 14/16 (87.5 %) | 0/8 (0 %) | 8/10 (80 %) | |