Table 4. Serum mediator profiles and NfL levels in patients with poor and good outcomes.

Mediators & NfL (pg/mL)	N (total)	Poor outcome N (%) = 16 (31.4)	Good outcome N (%) = 35 (68.6)	Total N = 51	p
IL-1RA	48 (94.1)	4419.9 (749.4–14088.5)	2601.2 (798.0–6699.1)	3341.2 (758.3–7131.7)	0.470
CCL11	48 (94.1)	185.4 (89.3–275.4)	98.7 (54.2–185.1)	113.6 (64.9–219.1)	0.038
CCL2	48 (94.1)	181.8 (119.9–427.3)	115.6 (61.4–213.1)	134.9 (67.1–269.2)	0.122
HGF	48 (94.1)	2489.4 (1253.0–6317.7)	858.7 (415.4–1610.2)	1168.3 (475.1–2497.0)	0.005
M-CSF	48 (94.1)	52.5 (21.8–81.6)	40.0 (18.1–56.7)	40.1 (19.4–61.5)	0.281
IL-6	48 (94.1)	12.4 (5.4–44.8)	8.8 (2.3–16.9)	9.2 (3.3–22.7)	0.164
IL-10	48 (94.1)	9.1 (2.4–28.9)	9.9 (2.8–18.6)	9.4 (2.6–27.2)	0.991
IFN-γ	45 (88.2)	0.6 (0.5–2.1)	1.1 (0.4–6.3)	0.9 (0.5–5.9)	0.455
TNF	47 (92.2)	10.0 (5.6–31.4)	14.2 (6.6–25.6)	11.0 (6.5–27.2)	0.825
IL-8	48 (94.1)	38.7 (15.4–146.9)	26.3 (11.6–137.3)	33.7 (12.9–139.7)	0.664
IL-17A	48 (94.1)	0.5 (0.3–0.9)	1.1 (0.5–6.8)	0.7 (0.5–4.4)	0.139
IL-6/IL-10	48 (94.1)	2.4 (0.9–5.9)	0.6 (0.3 to 1.2)	0.9 (0.4–2.4)	0.020
IL-17a/IL-10	48 (94.1)	0.1 (0.0–0.6)	0.2 (0.1– 0.4)	0.1 (0.1–0.4)	0.311
NfL	18 (35.3)	176.5 (113.5–799.5)	54.0 (22.8–150.5)	79.0 (22.8–155.0)	0.339

Note: Statistically significant p-values are marked in bold.

Abbreviations: CSF, cerebrospinal fluid; NfL, neurofilament.