Table 1. miRNAs targeting Wnt antagonist in ovarian cancer.
Non-coding RNAs | Cancer type | Function | Reference |
---|---|---|---|
miR-92a-1 | Epithelial Ovarian Cancer | Increased expression promotes oncogenic activation, & chemoresistance. Targets DKK1 | (Chen et al., 2017) |
miR-372 | Increased expression downregulates DKK1 activation | (Guan et al., 2017) | |
miR-126–5p | Increased expression represses DKK3, & promote platinum resistance | (Wu et al., 2019) | |
miR-1180 | Loss of tumour suppressor function, & promotes chemoresistance. Targets SFRP1 | (Gu et al., 2019) | |
miR-1207 | Promote cancer stem cell like fate & loss of tumour suppressor function. Targets SFRP1 | (Wu et al., 2015) | |
miR-181a | Increased chemoresistance and cancer stemness. Targets SFRP4 | (Nagaraj et al., 2021) |