Figure 4.

De novo designed peptide based antifouling coating. a) Conceptual design approach: the peptide design includes three functions: adsorption to the surface by a sticky amino acid, self-assembly motif of aromatic amino acids, and antifouling motif by incorporation of fluorine atoms. b) Chemical structure of the peptide NH₂–DOPA–(4F)Phe–(4F)Phe–COMe. c) Schematic presentation of spontaneous coating of the surface with a peptide monolayer by a dip-coating process. Figure 4 is based on data in ref. [70].