Figure 1. A) Current applications of tumor-derived organoids. B) Complex immune organoids can be used as platforms to test immunotherapies and include tumor stroma, immune cells and vasculature in addition to tumor tissue. Organoids cultures in microfluidic devices provide flow and structure and permit the combination of different organoid types. Organoid interactions with the surrounding tissue and vasculature can also be provided by the engraftment of organoids into tissue like the chicken chorioallantoic membrane (CAM).