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. Author manuscript; available in PMC: 2024 Dec 8.
Published in final edited form as: Nature. 2021 Mar 11;593(7857):136–141. doi: 10.1038/s41586-021-03412-7

Extended Data Fig. 8. Binding of human ACE2 to SARS-CoV-2 WT, N501Y, TM (N501Y, E484K, K417N) RBDs.

Extended Data Fig. 8

a-b. BLI binding analysis of the human ACE2 ectodomain (residues 1-615) to immobilized SARS-CoV-2 WT RBD (a) and B.1.1.7 RBD (b). Black lines correspond to a global fit of the data using a 1:1 binding model. RBD: receptor binding domain.