Extended Data Fig. 3. Representative neutralization curves of BNT162b2 vaccine sera against pseudovirus virus bearing eight Spike mutations present in B.1.1.7 versus wild type (all In Spike D614G background).

Indicated is serum log₁₀ inverse dilution against % neutralization. Where a curve is shifted to the right this indicates the virus is less sensitive to the neutralizing antibodies in the serum. Data are for first dose of vaccine (D1). Data points represent means of technical replicates and error bars represent standard error of the mean. Limit of detection for 50% neutralization set at 10.