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. Author manuscript; available in PMC: 2024 Dec 6.
Published in final edited form as: Nat Rev Chem. 2020 Sep 15;4(11):615–634. doi: 10.1038/s41570-020-0215-y

Table 1. Examples of peptides that form amyloid-like fibrils and hydrogels.

Peptide name Number of residues Associated protein/system Self-assembled structure Refs
Diphenylalanine (FF) 2 Aβ peptide Peptide nanotubes 28
α,β-Dehydrophenylalanine (ΔF) 2 Aβ peptide Hydrogel-forming fibrillar networks 34,35
Fmoc-FF-konjac glucomannan (KGM) 2 Aβ peptide Fibrillar hydrogels 36
FF-NH2 2 Aβ peptide Reversible peptide nanotubes/spheres 47,48
Ac-EFFAAE-NH2 (AIP-1/2) 6 Aβ peptide Amyloid fibrils 50
FFKLVFF 7 Aβ peptide Amyloid fibrils 3741
P11 (QQEFQWQFRQQ) 11 Aβ peptide Amyloid antiparallel β-sheet tapes 49,51