Table 1. Examples of peptides that form amyloid-like fibrils and hydrogels.
Peptide name | Number of residues | Associated protein/system | Self-assembled structure | Refs |
---|---|---|---|---|
Diphenylalanine (FF) | 2 | Aβ peptide | Peptide nanotubes | 28 |
α,β-Dehydrophenylalanine (ΔF) | 2 | Aβ peptide | Hydrogel-forming fibrillar networks | 34,35 |
Fmoc-FF-konjac glucomannan (KGM) | 2 | Aβ peptide | Fibrillar hydrogels | 36 |
FF-NH2 | 2 | Aβ peptide | Reversible peptide nanotubes/spheres | 47,48 |
Ac-EFFAAE-NH2 (AIP-1/2) | 6 | Aβ peptide | Amyloid fibrils | 50 |
FFKLVFF | 7 | Aβ peptide | Amyloid fibrils | 37–41 |
P11 (QQEFQWQFRQQ) | 11 | Aβ peptide | Amyloid antiparallel β-sheet tapes | 49,51 |