Table 3.
Results of the cross-validation analysis for extended models based on most predictive imaging variables. Error from each model cross-validation was reported together with its percentage change from the baseline model one for each of the endpoints.
| Model | Primary endpoint (Disease recurrence) |
Secondary endpoint (2y-DFS) |
||
|---|---|---|---|---|
| CV error | CV error change (%) from the Baseline Model | CV error | CV error change (%) from the Baseline Model | |
| Baseline Model | 0.240 | 0.0 | 0.174 | 0.0 |
| Baseline model extensions: | ||||
| Baseline T2w Energy, Baseline T2w Entropy | 0.186 | −22.8 | 0.142 | −18.3 |
| Baseline T2w Energy, Baseline T2w GLCM: Cluster Prominence | 0.181 | −24.5 | 0.148 | −14.9 |
| Baseline T2w Energy, Post CRT T2w GLRL: Low Gray-Level Run Emphasis | 0.201 | −16.2 | 0.168 | −3.2 |
| Baseline T2w Energy, Post CRT T2w GLRL: Run Percentage | 0.203 | −15.6 | 0.166 | −4.6 |
| Baseline T2w Energy, Baseline DWI Coefficient of Variation | 0.157 | −34.8 | 0.142 | −18.1 |
| Baseline T2w Energy, Baseline DWI Standard Variation | 0.183 | −23.7 | 0.217 | 24.7 |
| Baseline T2w Entropy, Baseline T2w GLCM: Cluster Prominence | 0.196 | −18.4 | 0.155 | −10.6 |
| Baseline T2w Entropy, Post CRT T2w GLRL: Low Gray-Level Run Emphasis | 0.221 | −8.2 | 0.173 | −0.2 |
| Baseline T2w Entropy, Post CRT T2w GLRL: Run Percentage | 0.222 | −7.8 | 0.172 | −1.3 |
| Baseline T2w Entropy, Baseline DWI Coefficient of Variation | 0.170 | −29.1 | 0.150 | −13.9 |
| Baseline T2w Entropy, Baseline DWI Standard Variation | 0.196 | −18.4 | 0.208 | 19.4 |
| Baseline T2w GLCM: Cluster Prominence, Post CRT T2w GLRL: Low Gray-Level Run Emphasis | 0.203 | −15.3 | 0.204 | 17.1 |
| Baseline T2w GLCM: Cluster Prominence, Post CRT T2w GLRL: Run Percentage | 0.205 | −14.6 | 0.208 | 19.8 |
| Baseline T2w GLCM: Cluster Prominence, Baseline DWI Coefficient of Variation | 0.171 | −28.7 | 0.173 | −0.3 |
| Baseline T2w GLCM: Cluster Prominence, Baseline DWI Standard Variation | 0.162 | −32.7 | 0.167 | −3.8 |
| Post CRT T2w GLRL: Low Gray-Level Run Emphasis, Post CRT T2w GLRL: Run Percentage | 0.257 | 6.8 | 0.208 | 19.7 |
| Post CRT T2w GLRL: Low Gray-Level Run Emphasis, Baseline DWI Coefficient of Variation | 0.178 | −25.7 | 0.151 | −13.0 |
| Post CRT T2w GLRL: Low Gray-Level Run Emphasis, Baseline DWI Standard Variation | 0.199 | −17.3 | 0.163 | −6.5 |
| Post CRT T2w GLRL: Run Percentage, Baseline DWI Coefficient of Variation | 0.179 | −25.3 | 0.152 | −12.8 |
| Post CRT T2w GLRL: Run Percentage, Baseline DWI Standard Variation | 0.200 | −16.6 | 0.163 | −6.3 |
| Baseline DWI Coefficient of Variation, Baseline DWI Standard Variation | 0.189 | −21.5 | 0.168 | −3.1 |
| Baseline T2w Energy | 0.188 | −21.7 | 0.121 | −30.3 |
| Baseline T2w Entropy | 0.203 | −15.4 | 0.134 | −22.6 |
| Baseline T2w GLCM: Cluster Prominence | 0.228 | −5.0 | 0.177 | 2.0 |
| Post CRT T2w GLRL: Low Gray-Level Run Emphasis | 0.247 | 3.0 | 0.198 | 14.1 |
| Post CRT T2w GLRL: Run Percentage | 0.248 | 3.3 | 0.201 | 15.4 |
| Baseline DWI Coefficient of Variation | 0.178 | −26.0 | 0.142 | −18.2 |
| Baseline DWI Standard Variation | 0.195 | −18.8 | 0.140 | −19.3 |