Skip to main content
. Author manuscript; available in PMC: 2024 Dec 7.
Published in final edited form as: Nature. 2019 Aug 21;573(7772):144–148. doi: 10.1038/s41586-019-1502-y

Extended Data Fig. 5. The unstructured LC-tails of Dhh1 are required for multivalent interactions underlying LLPS and PB formation.

Extended Data Fig. 5

(a) Larger field of view of the samples represented in Fig 1C. Scale bars 5 μm. Dcp2, the catalytic subunit of the Dcp1-Dcp2 mRNA decapping complex, is used as a marker of PBs. Representative images of > 4 independent experiments. (b) ClustalOmega sequence alignment of yeast DDXs and their human counterparts. The RecA core is displayed in green; asterisks indicate sequence identity, dots represent sequence similarity. (c) schematic representation of LC sequence distribution in the unstructured tails of A. thaliana DDXs. Clustal Omega alignment of Dhh1 with its three A. thaliana orthologues.