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. Author manuscript; available in PMC: 2024 Dec 7.
Published in final edited form as: Nat Chem Biol. 2019 Oct 21;15(12):1191–1198. doi: 10.1038/s41589-019-0384-5

Fig. 5. The concept of 5’-SS bulge repair.

Fig. 5

a, Ribbon representations of different RNA duplexes bound to U1-C zinc finger. On the left side, the structure was extracted from the crystal structure of U1 snRNP containing a canonical 5’-SS33. On the middle and right panels, the position of U1-C zinc finger was modelled on the solution structures of the RNA duplex or the RNA duplex bound to SMN-C5. b, Schematic representation of the 5’-SS bulge repair concept.