Table 2. PAF for dementia risk factors in India (n=2004).
RR for dementia (95% CI) | Risk factor prevalence2,8,10 | Communality | PAF | Weighted PAF* | |
---|---|---|---|---|---|
Early life (<45 years) | |||||
Low education | 1.6 (1.3–2.0) | 92.2% | 44% | 35.6% (33.5–37.7) | 13.6% (12.2–15.2) |
Midlife (45–64 years) | |||||
Hearing loss | 1.9 (1.4–2.7) | 22.3% | 37% | 16.7% (15.2–18.4) | 6.4% (5.4–7.6) |
Hypertension | 1.6 (1.2–2.2) | 19.3% | 60% | 10.4% (9.1–11.8) | 4.0% (3.2–4.9) |
Obesity | 1.6 (1.3–1.9) | 13.7% | 64% | 7.6% (6.5–8.8) | 2.9% (2.2–3.7) |
Later life (≥65 years) | |||||
Smoking | 1.6 (1.2–2.2) | 39.9% | 68% | 19.3% (17.6–21.1) | 6.4% (5.4–7.6) |
Depression | 1.9 (1.6–2.3) | 5.2% | 72% | 4.5% (3.7–5.5) | 1.7% (1.2–2.4) |
Physical inactivity | 1.4 (1.2–1.7) | 15.3% | 78% | 8.4% (7.3–9.7) | 2.2% (1.6–2.9) |
Low social contact | 1.6 (1.3–1.9) | 10.4% | 57% | 4.0% (3.2–4.9) | 2.3% (1.7–3.1) |
Diabetes | 1.5 (1.3–1.8) | 9.3% | 52% | 4.4% (3.6–5.4) | 1.7% (1.2–2.4) |
Overall weighted PAF | .. | .. | .. | .. | 41.2% (39.1–43.4) |
PAF=population attributable fraction. RR=relative risk.
Weighted PAF is the relative contribution of each risk factor to the overall PAF when adjusted for communality.