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. Author manuscript; available in PMC: 2024 Dec 9.
Published in final edited form as: Lancet Glob Health. 2019 May 1;7(5):e596–e603. doi: 10.1016/S2214-109X(19)30074-9

Table 2. PAF for dementia risk factors in India (n=2004).

RR for dementia (95% CI) Risk factor prevalence2,8,10 Communality PAF Weighted PAF*
Early life (<45 years)
   Low education 1.6 (1.3–2.0) 92.2% 44% 35.6% (33.5–37.7) 13.6% (12.2–15.2)
Midlife (45–64 years)
   Hearing loss 1.9 (1.4–2.7) 22.3% 37% 16.7% (15.2–18.4) 6.4% (5.4–7.6)
   Hypertension 1.6 (1.2–2.2) 19.3% 60% 10.4% (9.1–11.8) 4.0% (3.2–4.9)
   Obesity 1.6 (1.3–1.9) 13.7% 64% 7.6% (6.5–8.8) 2.9% (2.2–3.7)
Later life (≥65 years)
   Smoking 1.6 (1.2–2.2) 39.9% 68% 19.3% (17.6–21.1) 6.4% (5.4–7.6)
   Depression 1.9 (1.6–2.3) 5.2% 72% 4.5% (3.7–5.5) 1.7% (1.2–2.4)
   Physical inactivity 1.4 (1.2–1.7) 15.3% 78% 8.4% (7.3–9.7) 2.2% (1.6–2.9)
   Low social contact 1.6 (1.3–1.9) 10.4% 57% 4.0% (3.2–4.9) 2.3% (1.7–3.1)
   Diabetes 1.5 (1.3–1.8) 9.3% 52% 4.4% (3.6–5.4) 1.7% (1.2–2.4)
Overall weighted PAF .. .. .. .. 41.2% (39.1–43.4)

PAF=population attributable fraction. RR=relative risk.

*

Weighted PAF is the relative contribution of each risk factor to the overall PAF when adjusted for communality.