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. Author manuscript; available in PMC: 2024 Dec 9.
Published in final edited form as: Nat Neurosci. 2018 Nov 26;21(12):1742–1752. doi: 10.1038/s41593-018-0278-y

Figure 7. Changes in the properties of epileptic bursts between clusters of seizures.

Figure 7

(a) With the approaching cluster the duration of the bursts increase (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P=0.012), as well as, the line length parameter (b) (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P=0.016). (c) The proximity to critical transition is also marked by the increasing rate of epileptic bursts (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,59)=, P=0.005). (d) Increase in spatial correlation reflects enhanced propagation of bursts to the hippocampus and motor cortex increased (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P=0.001). (e) The autocorrelation (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P=0.928), signal variance (f) (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P =0.814) and the first spectral moment (g) (n=6/6 intercluster periods/animals, one-way ANOVA, F(1,53)=, P =0.128) did not show significant changes with approaching cluster. The significance of changes in temporal profiles was analyzed using one-way ANOVA. Circles and error bars represent mean and s.e.m. respectively.