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. Author manuscript; available in PMC: 2024 Dec 11.
Published in final edited form as: Drug Discov Today. 2018 May 7;23(6):1293–1304. doi: 10.1016/j.drudis.2018.05.012

Figure 5.

Figure 5

Naringin therapeutic activity in disuse osteoporosis induced by unilateral sciatic neurectomy (USN). (A) Representative 3D images showing the trabecular microarchitecture in the distal femoral metaphysis of each group. (B) Immunohistochemical staining of OC and osteoclasts (TRAP+) in the distal femoral metaphysis, as well as histomorphometric analysis of naringin-prevented deterioration of the ipsilateral femurs due to immobilization. Adapted from reference [49] under a Creative Commons Attribution 4.0 International license (https://creativecommons.org/licenses/by/4.0/).