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. Author manuscript; available in PMC: 2025 Mar 31.
Published in final edited form as: Heart. 2025 Jun 13;111(13):618–625. doi: 10.1136/heartjnl-2024-324618

Table 2. Prevalence and odds ratio of health condition groups in adults with atrial fibrillation compared to adults without atrial fibrillation.

Health condition Adults with AF
n (%)
(N=34,338)
Adults without AF
n (%)
(N=907,739)
Unadjusted OR
(95%CI)
OR adjusted for
age and sex
(95%CI)
OR adjusted for
age, sex and IMD
(95%CI)
Abnormal lipid level 17906 (52.1) 360518 (39.7) 1.65 (1.62-1.69) 0.49 (0.47-0.50) 0.48 (0.47-0.50)
Benign neoplasm 7957 (23.2) 115993 (12.8) 2.06 (2.01-2.11) 1.07 (1.04-1.10) 1.08 (1.05-1.11)
Cardiovascular 30688 (89.4) 236587 (26.1) 23.85 (23.04-24.70) 5.82 (5.60-6.05) 5.81 (5.59-6.03)
Dermatological 16735 (48.7) 387303 (42.7) 1.28 (1.25-1.31) 1.43 (1.40-1.46) 1.44 (1.40-1.47)
Ear nose throat disorder 14770 (43.0) 279142 (30.8) 1.70 (1.66-1.74) 1.23 (1.20-1.26) 1.24 (1.21-1.27)
Endocrine and diabetes 13395 (39.0) 143622 (15.8) 3.40 (3.33-3.48) 1.55 (1.51-1.59) 1.54 (1.50-1.58)
Eye disorder 16494 (48.0) 119496 (13.2) 6.10 (5.96-6.23) 1.42 (1.39-1.46) 1.42 (1.38-1.45)
Gastrointestinal 21246 (61.9) 337617 (37.2) 2.74 (2.68-2.80) 1.34 (1.31-1.38) 1.34 (1.31-1.37)
Genito urinary 14029 (40.9) 151612 (16.7) 3.45 (3.37-3.52) 1.23 (1.20-1.26) 1.23 (1.20-1.26)
Gynaecological 4885 (14.2) 157731 (17.4) 0.79 (0.76-0.81) 0.82 (0.79-0.85) 0.82 (0.79-0.85)
Haematological 9987 (29.1) 103393 (11.4) 3.19 (3.11-3.27) 1.93 (1.88-1.98) 1.92 (1.87-1.97)
Infectious disease 16254 (47.3) 122871 (13.5) 5.74 (5.62-5.87) 3.14 (3.07-3.22) 3.13 (3.06-3.21)
Liver disorder 1149 (3.3) 13067 (1.4) 2.37 (2.23-2.52) 1.48 (1.38-1.57) 1.45 (1.36-1.55)
Mental health 14001 (40.8) 286717 (31.6) 1.49 (1.46-1.52) 1.26 (1.23-1.29) 1.24 (1.21-1.27)
Neurological 7454 (21.7) 135081 (14.9) 1.59 (1.54-1.63) 1.30 (1.27-1.34) 1.30 (1.26-1.33)
Orthopaedic 19856 (57.8) 213466 (23.5) 4.46 (4.36-4.56) 1.32 (1.29-1.35) 1.32 (1.28-1.35)
Primary dermatological malignancy 4183 (12.2) 28496 (3.1) 4.28 (4.13-4.43) 1.09 (1.05-1.14) 1.10 (1.06-1.14)
Primary haematological malignancy 825 (2.4) 5705 (0.6) 3.89 (3.61-4.19) 1.48 (1.37-1.60) 1.48 (1.37-1.60)
Primary solid organ malignancy 5217 (15.2) 41481 (4.6) 3.74 (3.63-3.86) 1.06 (1.03-1.10) 1.07 (1.03-1.10)
Renal 18617 (54.2) 111990 (12.3) 8.41 (8.23-8.60) 2.22 (2.17-2.28) 2.21 (2.16-2.27)
Respiratory 14702 (42.8) 186492 (20.5) 2.90 (2.83-2.96) 2.52 (2.46-2.58) 2.51 (2.45-2.57)
Rheumatological 17325 (50.5) 252637 (27.8) 2.64 (2.58-2.70) 1.03 (1.01-1.06) 1.04 (1.01-1.06)
Secondary malignancy 1261 (3.7) 9791 (1.1) 3.50 (3.29-3.71) 1.06 (1.00-1.13) 1.06 (0.99-1.13)