Table 4. Prevalence and odds ratio of the twenty most common non-cardiovascular health conditions in adults with atrial fibrillation compared to adults without atrial fibrillation.
| Health condition | Adults with AF, n (%) (N=34,338) |
Adults without AF, n (%) (N=907,739) |
Unadjusted OR (95%CI) |
OR adjusted for age and sex (95%CI) |
OR adjusted for age, sex and IMD (95%CI) |
|---|---|---|---|---|---|
| Osteoarthritis | 15120 (44.0) | 126637 (14.0) | 4.85 (4.75-4.96) | 1.12 (1.10-1.15) | 1.12 (1.09-1.15) |
| Chronic kidney disease |
13924 (40.5) | 70064 (7.7) | 8.15 (7.97-8.34) | 1.92 (1.87-1.97) | 1.91 (1.86-1.96) |
| Enthesopathies and synovial disorders |
12801 (37.3) | 207303 (22.8) | 2.01 (1.96-2.05) | 0.85 (0.83-0.87) | 0.85 (0.83-0.87) |
| Cataract | 11649 (33.9) | 63595 (7.0) | 6.82 (6.65-6.98) | 1.29 (1.25-1.32) | 1.29 (1.25-1.32) |
| Other infection | 10945 (31.9) | 69300 (7.6) | 5.66 (5.53-5.80) | 3.18 (3.10-3.26) | 3.16 (3.08-3.24) |
| Dermatitis (atopic/ contact/ other/ unspecified) |
10629 (31.0) | 235761 (26.0) | 1.28 (1.25-1.31) | 1.34 (1.31-1.38) | 1.35 (1.31-1.38) |
| Raised cholesterol | 10515 (30.6) | 280223 (30.9) | 0.99 (0.97-1.01) | 0.36 (0.35-0.37) | 0.36 (0.35-0.37) |
| Raised LDL (low-density lipoprotein) cholesterol |
9912 (28.9) | 239899 (26.4) | 1.13 (1.10-1.16) | 0.44 (0.43-0.46) | 0.45 (0.43-0.46) |
| Bacterial diseases (excluding tuberculosis) | 9139 (26.6) | 53800 (5.9) | 5.76 (5.61-5.90) | 2.64 (2.57-2.71) | 2.62 (2.55-2.70) |
| Urinary tract infections | 8453 (24.6) | 40778 (4.5) | 6.94 (6.76-7.13) | 2.57 (2.50-2.65) | 2.56 (2.49-2.63) |
| Acute kidney injury | 8159 (23.8) | 25371 (2.8) | 10.84 (10.54-11.14) | 2.76 (2.68-2.85) | 2.76 (2.68-2.85) |
| Gastro oesophageal reflux disease, oesophagitis and oesophageal ulcer |
8102 (23.6) | 109975 (12.1) | 2.24 (2.18-2.30) | 1.08 (1.05-1.11) | 1.07 (1.04-1.10) |
| Hearing loss | 8079 (23.5) | 82363 (9.1) | 3.08 (3.00-3.16) | 1.33 (1.30-1.37) | 1.33 (1.29-1.37) |
| Lower respiratory tract infections | 7559 (22.0) | 32827 (3.6) | 7.52 (7.32-7.73) | 2.84 (2.76-2.93) | 2.84 (2.75-2.93) |
| Depression | 7373 (21.5) | 187762 (20.7) | 1.05 (1.02-1.08) | 0.95 (0.92-0.98) | 0.93 (0.91-0.96) |
| Abdominal hernia | 6437 (18.7) | 67596 (7.4) | 2.87 (2.79-2.95) | 1.27 (1.23-1.31) | 1.27 (1.23-1.31) |
| Hyperplasia of prostate | 6195 (18.0) | 32634 (3.6) | 5.90 (5.73-6.08) | 1.16 (1.12-1.21) | 1.17 (1.12-1.21) |
| Type 2 diabetes mellitus | 6629 (19.3) | 51293 (5.7) | 3.99 (3.88-4.11) | 1.25 (1.21-1.28) | 1.23 (1.20-1.27) |
| Anxiety disorders | 5833 (17.0) | 141632 (15.6) | 1.11 (1.08-1.14) | 1.02 (0.99-1.06) | 1.01 (0.98-1.04) |
| Low HDL (high-density lipoprotein) cholesterol |
5820 (16.9) | 71571 (7.9) | 2.38 (2.32-2.45) | 1.33 (1.29-1.38) | 1.32 (1.28-1.36) |
AF= atrial fibrillation; CI= confidence interval; IMD= Index of Multiple Deprivation; OR= odds ratio.