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. 2025 Apr 6;56(6):1542–1553. doi: 10.1161/STROKEAHA.124.049808

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© 2025 The Authors.

Stroke is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited.

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Figure 5. — Comparison of the associations between genetic proxies for coagulation cascade protein levels and risk of ischemic stroke and venous thromboembolism (VTE). The VTE Z score is displayed on the x axis, and the ischemic stroke Z score is displayed on the y axis. The dotted blue lines correspond to a Z score of 3.15, which corresponds to the P value cutoff of 0.0017 used in the present study. Each dot represents a single variant, with red dots highlighting proxies significantly associated with ischemic stroke. Bottom focuses on a narrower range of VTE Z scores for clearer visualization.