Table 7. Changes in corneal fluorescein score following exosomes treatment.

Study	DED model type and treatment route	DED treated with Exosomes	DED given PBS/saline	Absolute difference between PBS group and exosomes	Healthy control	Absolute difference between exosome and healthy control
Tian et al. 2023 *	C57BL/6 mice BAC model, topical	MSC-Exo; 6MSC-Exo- Ce; 2	12.5	10.5−6.5	0.5	1.5−5.5
Ma et al.2023 *	C57BL/6 mice BAC model, topical	mExo; 7.5mExo@AA; 4	15	7.5−11	1	3−6.5
Wang et al. 2022*	C57BL/6 mice BAC model, topical	1.8	3.5	1.7	0.5	1.3
Guo et al. 2022 *	C57BL/6 mice BAC model, topical	3	5	2	0.5	2.5
Wang et al.2023 *	C57BL/6 mice BAC model, topical	2 in 3.0 mg/mL Exo group	8	6	N/A
Yu et al.2020	C57BL/6 mice BAC model, topical	5.2	12.0	6.8	1.2	4

^*Values obtained from the graph as no absolute values given in the article

DED- Dry Eye Disease, PBS − Phosphate Buffer Solution, BAC − Benzalkonium Chloride, MSC − Mesenchymal Stem Cell