Table 3. Trial outcomes by HIV status and sex.

	Intervention	Control	Cluster-level geometric mean prevalence (GSD)		Adjusted risk ratio* (95% CI)	p value	Test for interaction (p value)
			Intervention (n=8)	Control (n=8)
C trachomatis, N gonorrhoeae, and T vaginalis†	··	··	··	··	··	··	0·68
HIV-positive	47/156	69/208	26·35% (1·81)	30·17% (1·52)	0·85 (0·50–1·44)	0·51	··
HIV-negative	487/2583	497/2612	18·46% (1·21)	18·99% (1·09)	0·94 (0·79–1·11)	0·41	··
C trachomatis ‡	··	··	··	··	··	··	0·43
HIV-positive	24/156	43/213	16·30% (1·77)	19·81% (1·70)	0·81 (0·45–1·43)	0·43	··
HIV-negative	333/2583	338/2684	12·79% (1·14)	12·49% (1·16)	0·99 (0·86–1·14)	0·89	··
N gonorrhoeae ‡	··	··	··	··	··	··	0·016
HIV-positive	9/156	9/205	6·44% (2·54)	5·65% (2·16)	1·14 (0·47–2·80)	0·75	··
	43/2583	76/2599	1·43% (1·84)	2·82% (1·39)	0·50 (0·29–0·86)	0·017	··
T vaginalis ‡	··	··	··	··	··	··	0·84
HIV-positive	28/156	32/213	16·58% (2·25)	15·15% (1·46)	1·04 (0·58–1·86)	0·89	··
HIV-negative	182/2583	155/2684	6·48% (1·45)	5·60% (1·32)	1·10 (0·76–1·58)	0·60	··
C trachomatis, N gonorrhoeae, and T vaginalis†	··	··	··	··	··	··	0·95
Male	116/953	144/1148	11·14% (1·30)	12·41% (1·22)	0·90 (0·72–1·12)	0·32	··
Female	422/1803	425/1697	22·71% (1·22)	25·09% (1·14)	0·91 (0·75–1·09)	0·28	··
C trachomatis ‡	··	··	··	··	··	··	0·98
Male	78/953	101/1176	7·44% (1·34)	7·80% (1·61)	0·95 (0·68–1·34)	0·77	··
Female	280/1803	281/1746	15·45% (1·13)	16·10% (1·10)	0·96 (0·85–1·09)	0·51	··
N gonorrhoeae ‡	··	··	··	··	··	··	0·63
Male	17/953	28/1143	1·39% (1·79)	2·30% (1·66)	0·60 (0·33–1·10)	0·092	··
Female	35/1803	57/1686	1·61% (2·06)	3·21% (1·53)	0·50 (0·27–0·95)	0·036	··
T vaginalist	··	··	··	··	··	··	0·055
Male	34/953	23/1176	3·83% (1·38)	1·92% (2·10)	2·00 (1·08–3·71)	0·031	··
Female	179/1803	166/1746	8·82% (1·49)	9·10% (1·46)	0·97 (0·63–1·50)	0·90	··
C trachomatis and N gonorrhoeae§	··	··	··	··	··	··	0·48
Male	89/953	123/1145	8·31% (1·38)	10·34% (1·37)	0·80 (0·59–1·09)	0·14	··
Female	304/1803	316/1694	16·72% (1·15)	18·70% (1·14)	0·89 (0·77–1·04)	0·14	··

C trachomatis=Chlamydia trachomatis. GSD=geometric standard deviation. N gonorrhoeae=Neisseria gonorrhoeae. T vaginalis=Trichomonas vaginalis.

^*Adjusted for sex and age in years.

^†Population-level prevalence of any (one or more) of C trachomatis, N gonorrhoeae, and T vaginalis.

^‡Population-level prevalence of single infection.

^§Population-level prevalence of one or both of C trachomatis and N gonorrhoeae.