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. Author manuscript; available in PMC: 2026 May 15.
Published in final edited form as: Sex Transm Dis. 2025 Sep 9;53(1):20–27. doi: 10.1097/OLQ.0000000000002242

Table 4. Multivariable predictors of willingness for mpox vaccination among men who have sex with men (MSM, n=250) and transgender women (TGW, n=251).

Predictors Model 4.1. Mpox Vaccination
Willingness among MSM & TGW
Model 4.2. Mpox Vaccination
Willingness among MSM
Model 4.3. Mpox Vaccination
Willingness among TGW
PRRa 95% CI p PRR 95% CI p PRR 95% CI p
Sociodemographics
Age (years) 1.01 0.99 – 1.03 0.35 1.00 0.98 – 1.02 0.85 1.00 0.97 – 1.03 0.92
Education: ≥ Higher secondary (Ref.: ≤ 10th grade) 0.80 0.63 – 1.02 0.07 0.94 0.74 – 1.21 0.66 0.65 0.42 – 1.03 0.06
Recruitment: Online (Ref.: Offline) 1.52 1.19 – 1.93 0.001 0.71 0.54 – 0.94 0.018 15.20 5.25 – 43.98 <0.001
Subgroup: TGW (Ref.: MSM) 0.43 0.30 – 0.60 <0.001
Awareness of mpox and PrEP
Prior awareness of Mpox – Yes (Ref.: No) 1.12 0.85 – 1.47 0.40 1.25 0.94 – 1.65 0.12 1.25 0.70 – 2.20 0.44
Awareness of burden of mpox among MSM/TGW – Yes (Ref.: No) 1.31 1.01 – 1.69 0.041 1.06 0.81 – 1.38 0.66 2.05 1.28 – 3.30 0.003
PrEP awareness - Yes (Ref.: No) 0.94 0.75 – 1.17 0.59 0.90 0.72 – 1.13 0.36 0.94 0.57 – 1.55 0.80
HIV/STI risk
Sex work in the past month - Yes (Ref.: No) 1.01 0.75 – 1.35 0.96 0.87 0.67 – 1.13 0.28 1.54 0.83 – 2.87 0.17
Inconsistent condom use with any male partner - Yes (Ref.: No) 0.68 0.53 – 0.87 0.002 0.84 0.66 – 1.07 0.16 0.68 0.41 – 1.12 0.13
Psychosocial problems
Anxiety - Yes (Ref.: No) 1.13 0.85 – 1.49 0.39 1.21 0.94 – 1.57 0.14 0.85 0.49 – 1.49 0.57
Depression - Yes (Ref.: No) 0.68 0.49 – 0.94 0.020 1.05 0.76 – 1.45 0.75 0.92 0.55 – 1.54 0.75
Health Protection Behavior
COVID vaccinated - Yes (Ref.: No) 0.73 0.50 – 1.07 0.11 0.70 0.44 – 1.12 0.13 0.82 0.49 – 1.38 0.46
a

Prevalence Rate Ratio

Note. Estimates are from multivariable modified Poisson regression models with robust standard errors. Model 4.1 was adjusted for all variables listed in the table. Models 4.2 and 4.3 were adjusted for all variables listed, excluding ‘Subgroup’. PrEP: Pre-Exposure Prophylaxis.