Table 1. Demographic details of the two groups.
| Variable | Controls (N = 25), Mean (SD) | Patients (N = 33), Mean (SD) | p value |
|---|---|---|---|
| Age (years) | 76.9 (6.0) | 77.3 (6.4) | 0.803 |
| Gender (female, %) | 56.0 % | 60.6 % | 0.742 |
| Height (cm) | 167.7 (10.2) | 169.6 (9.6) | 0.481 |
| Weight (kg) | 67.2 (11.3) | 74.7 (18.1) | 0.197 |
| Concern about falling (Short FES-I, 7–28) | 7.6 (1.0) | 13.9 (4.8) | <0.001 |
| Anxiety (HADS-A, 0–21) | 2.8 (2.3) | 6.6 (4.4) | 0.001 |
| Depression (HADS-D, 0–21) | 2.7 (3.1) | 6.3 (3.7) | <0.001 |
| Dizziness handicap (DHI, 0-100) | 0.2 (0.7) | 33.6 (18.7) | <0.001 |
| Short Physical Performance Battery (0–12, higher = better) | 11.2 (1.0) | 9.7 (2.1) | 0.003 |
| Ankle vibration perceptual threshold (0–8, arb. units; higher = better) | 4.50 (2.17) | 3.48 (2.02) | 0.051 |
| WMH (volume/ml)* | 9.36 (9.02) | 14.41 (19.42) | 0.441 |
| Number of lesions* | 13.71 (8.47) | 14.32 (6.12) | 0.764 |
| Mean FA (lower values suggest reduced white matter structural integrity)* | 0.439 (0.061) | 0.442 (0.055) | 0.865 |
FES-I = Falls Efficacy Scale—International; HADS-A = Hospital Anxiety and Depression Scale, Anxiety; HADS-D = Hospital Anxiety and Depression Scale, Depression; DHI = Dizziness Handicap Inventory; VSS = Vertigo Symptoms Scale; WMH = white matter hyperintensity; FA = fractional anisotropy.
Note, MRI data were only available for 24 Controls and 28 Patients.