TABLE 2.
Radiation dosimetry estimates per Unit Administered Activity for 18F-VM4–037 for the Human Adult Male Phantom in 1- and 4.8-Hour Bladder-Voiding Models, Based on Human Biodistribution Data
| 1 hr Void | 4.8 hr Void | |
|---|---|---|
| Organ | (μGy/MBq) | (μGy/MBq) |
| Kidneys | 273±31 | 273±31 |
| Liver | 240±68 | 240±68 |
| Gallbladder Wall | 63±17 | 63±17 |
| Adrenals | 31±4.3 | 31±4.3 |
| Pancreas | 26±3.3 | 26±3.3 |
| Upper Large Intestine Wall | 17±1.8 | 17±1.8 |
| Heart Wall | 15±1.6 | 15±1.6 |
| Spleen | 14±1.4 | 14±1.5 |
| Urinary Bladder Wall | 14±2.2 | 41±5.7 |
| Lungs | 13±1.4 | 13±1.4 |
| Small Intestine | 13±1.1 | 13±1.1 |
| Stomach Wall | 13±0.8 | 13±0.8 |
| Lower Large Intestine Wall | 12±7.5 | 13±7.6 |
| Red Marrow | 9.3±0.6 | 9.4±0.5 |
| Osteogenic Cells | 8±1.5 | 8.1±1.5 |
| Muscle | 7.6±0.6 | 7.8±0.6 |
| Ovaries | 6.8±1.6 | 7.5±1.6 |
| Uterus | 6.5±1.5 | 8.1±1.6 |
| Breasts | 6.4±0.3 | 6.4±0.3 |
| Thymus | 6±0.7 | 6±0.7 |
| Skin | 4.7±0.6 | 4.7±0.6 |
| Thyroid | 3.2±1.4 | 3.2±1.4 |
| Testes | 2.9±1.5 | 3.4±1.5 |
| Brain | 1.7±0.7 | 1.7±0.7 |
| Total Body | 15±1.4 | 15±1.4 |
| Effective Dose (μSv/MBq) | 26±1 | 28±1 |
Data are mean ± SD; n=4