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. 2020 Oct 23;44(6):2678–2690. doi: 10.3892/or.2020.7824

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Copyright: © Guo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — SP1 is upregulated and miR-7 is downregulated in NSCLC tissues. (A) SP1 transcript expression in LUSC, LUAD, and normal tissues and SP1 protein expression in LUAD tissues and normal tissues. (B) SP1 expression was examined in 8 cases of NSCLC tissues and adjacent normal tissues by western blotting. N indicates normal tissues and C indicates cancer tissues. (C) SP1 expression was examined in 95 cases of NSCLC tissues and adjacent non-cancer tissues by IHC staining. The brown granules in the image are strongly positive in the nucleus (magnification, ×100). (D) miR-7 expression in primary NSCLC tissues and matched adjacent lung tissues. ***P<0.001. SP1, specific protein 1; miR-7, microRNA-7; NSCLC, non-small cell lung cancer; LUADC, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; IHC, immunohistochemical.