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. Author manuscript; available in PMC: 2020 Nov 4.
Published in final edited form as: Stem Cells. 2014 May;32(5):1361–1366. doi: 10.1002/stem.1635

Figure 4.

Figure 4.

Myelodysplastic syndromes in p15Ink4bfl/flNHD13 mice and acute T-ALL in Nup98-HoxD13 (NHD13) mice. (A): Diff-Quick-stained smears of peripheral blood of p15Ink4bfl/flNHD13 mice showing: (i) poikilocytosis, (ii) Howell-Jolly bodies, and (iii) cells with multiple nuclei. Diff-Quick-stained smears of bone marrow showing: (iv) hypolobulated megakaryocyte and (v) cells with abnormal nuclear maturation. (B): Increased numbers of CD4/CD8 double positive cells in the bone marrow and spleen of NHD13 mice. H&E staining of liver sections showing metastasis adjacent to large blood vessels. Staining of the liver sections for CD3 and MPO. Abbreviation: T-ALL, acute T lymphoblastic leukemia.