Fig. 4.

A-HDL remodeling promotes CLP-induced deregulation of pulmonary endothelium. a Representative immunohistochemistry of VCAM1 on lung sections from C57BL/6 and apoA-I KO mice treated with PBS, N-HDL or A-HDL after CLP. b Immunoblot analyses and the ratio of densitometric measurement to GAPDH are represented by the bar graphs (n = 3–5 per group). *p < 0.05 versus sham group; ^#p < 0.05 versus PBS treatment group; ^&p < 0.05 versus N-HDL treatment group. CLP: Cecal ligation and puncture, VCAM1: vascular cell adhesion molecule-1, ICAM1: intercellular adhesion molecules-1, N-HDL: the HDL from normal subjects, A-HDL: the HDL from ARDS patients. Scale bar: 100 μm