Table 1.
Characteristics of the studies with lesion response and lesion size changes after PDT
| Author | Year | Light sources | Photosensitizer | Lesion types | Administration Method | Lesion locations | Sample size | CR | PR | lesion size of pre-PDT | lesion size of post-PDT | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | ||||||||||
| Aghahosseini F | 2006 | diode laser | MB | mixed | gargle | mixed | 26 | 4 | 12 | 1.8 | 0.7 | 1 | 0.9 |
| Sadaksharam J | 2012 | xenon lamp | MB | mixed | gargle | mixed | 20 | 0 | 10 | ||||
| Sobaniec S | 2013 | semiconductor laser | chlorin e6 derivative | mixed | topical | mixed | 48 | 14 | 25 | 6 | 4.5 | 2.7 | 2.62 |
| BM/L | 40 | 13 | 22 | 6.6 | 4.63 | 2.8 | 2.81 | ||||||
| T/G | 8 | 1 | 3 | 3 | 1.9 | 2.1 | 1.21 | ||||||
| Prasanna SW | 2015 | metal halide lamp | MB | mixed | gargle | mixed | 15 | 0 | 13 | 3 | 1.6 | 0.8 | 1 |
| Maloth KN | 2016 | LED | 5-ALA | mixed | topical | mixed | 10 | 0 | 8 | 2.22 | 0.79 | 1.41 | 0.74 |
| Bakhtiari S | 2017 | LED | MB | mixed | gargle | mixed | 15 | 0 | 2 | ||||
| Mostafa D | 2017 | diode laser | MB | mixed | gargle | mixed | 19 | 7 | 9 | ||||
| Sulewska M | 2017 | LED | 5-ALA | erosive | topical | mixed | 22 | 5 | 11 | 1.49 | 1.45 | 1.37 | 1.78 |
| BM | 16 | 4 | 7 | 1.06 | 0.98 | 1.08 | 1.57 | ||||||
| T /G | 6 | 1 | 4 | 2.63 | 1.93 | 2.13 | 2.24 | ||||||
| Rakesh N | 2018 | diode laser | 5-ALA | erosive | topical | mixed | 10 | 0 | 10 | ||||
| Sulewska M | 2019 | LED | 5-ALA | reticular | topical | mixed | 124 | 46 | 63 | 3.99 | 3.73 | 1.48 | 1.98 |
| BM | 80 | 27 | 44 | 4.58 | 4.01 | 1.67 | 2.04 | ||||||
| T /G | 44 | 19 | 19 | 2.93 | 2.91 | 1.13 | 1.84 | ||||||
PDT Photodynamic therapy, GaAlAs Gallium-Aluminum-Arsenide, LED Light emitting diode, TB Toluidine blue, 5-ALA 5 aminolevulinic acid, MB Methylene Blue, BM/L Buccal mucosa and/or lips, T/G Tongue and/or gingival mucosa; mixed: with different required information or information were not mentioned, CR Complete response, PR Partial response, NR No response, SD Standard deviation