Table 1.
Demographic and Tumor Variables Stratified by Sex for 16,807 Cutaneous Melanoma Patients
| Male (n = 10,111) | Female (n = 6,696) | pa | |
|---|---|---|---|
| Age, median (interquartile range) | 64 (54 − 74) | 64 (51 − 78) | 0.0706 |
| Race, n (%) | <0.0001 | ||
| Non-Hispanic White | 9,607 (95.0) | 6,214 (92.8) | |
| Hispanic | 162 (1.6) | 219 (3.3) | |
| Non-Hispanic Black | 30 (0.3) | 29 (0.4) | |
| Non-Hispanic Asian or Pacific Islander | 161 (1.6) | 127 (1.9) | |
| Other or unknown | 151 (1.5) | 107 (1.6) | |
| Anatomic location (primary tumor), n (%) | <0.0001 | ||
| Head/neck | 2,413 (23.9) | 860 (12.8) | |
| Trunk | 3,247 (32.1) | 2,242 (33.5) | |
| Upper extremity | 1,933 (19.1) | 1,388 (20.7) | |
| Lower extremity | 1,109 (11.0) | 1,566 (23.4) | |
| Other or not specified | 1,409 (13.9) | 640 (9.6) | |
| Tumor thickness (Breslow depth), n (%) | <0.0001 | ||
| ≤1.0 mm | 1,171 (11.6) | 567 (8.5) | |
| 1.01 − 2.00 mm | 1,441 (14.3) | 1,032 (15.4) | |
| 2.01 − 4.00 mm | 3,297 (32.6) | 2,010 (30.0) | |
| ≥4.00 mm | 2,506 (24.8) | 1,508 (22.5) | |
| Missing | 1,696 (16.8) | 1,579 (23.6) | |
| T classification, n (%) | <0.0001 | ||
| T0 (unknown primary) | 937 (9.3) | 392 (5.9) | |
| T1 | 596 (5.9) | 317 (4.7) | |
| T2 | 1,627 (16.1) | 1,427 (21.3) | |
| T3 | 3,644 (36.0) | 2,524 (37.7) | |
| T4 | 2,686 (26.6) | 1,705 (25.5) | |
| Tx (T stage missing) | 621 (6.1) | 331 (4.9) | |
| Ulceration (primary tumor), n (%) | <0.0001 | ||
| Present | 4,189 (41.4) | 2,607 (38.9) | |
| Absent | 3,649 (36.1) | 2,268 (33.9) | |
| Unknown | 2,273 (22.5) | 1,821 (27.2) | |
| Mitotic rate, mitoses/mm2 (primary tumor), n (%) | <0.0001 | ||
| 0, <1 | 563 (5.6) | 392 (5.9) | |
| 1 | 902 (8.9) | 621 (9.3) | |
| ≥2 | 4,997 (49.4) | 3,058 (45.7) | |
| Unknown | 3,649 (36.1) | 2,625 (39.2) | |
| Pathologic lymph node status, n (%) | 0.0050 | ||
| Node negative | 5,885 (58.2) | 3,915 (58.5) | |
| Node positive | 3,412 (33.8) | 2,330 (34.8) | |
| No pathologic nodal staging | 814 (8.1) | 451 (6.7) | |
| N classification, n (%) | <0.0001 | ||
| N0 | 5,885 (58.2) | 3.915 (58.5) | |
| N1 | 1,574 (15.6) | 1,022 (15.3) | |
| N2 | 982 (9.7) | 547 (8.2) | |
| N3 | 856 (8.5) | 761 (11.4) | |
| NX (not staged) | 814 (8.1) | 451 (6.7) | |
a
p Value for comparisons between male and female patients for each variable.