Table 2.

Methylation of LINE-1 and MGMT and H3K36me3 modification in two groups of workers

Epigenetic modifications	Control group		PAH-exposed group		P b
	N a	Median (IQR)	N a	Median (IQR)
LINE-1 (% 5mC)	94	83.66 (82.07–85.84)	169	80.42 (78.90–82.84)	<0.001
MGMT (% 5mC)	92	5.51 (3.61–7.21)	168	3.26 (2.78–4.30)	<0.001
H3K36me3 (relative %)	94	7.35 (4.00–11.15)	173	12.58 (8.36–18.99)	<0.001

ELISA, sandwich enzyme-linked immunosorbent assay; 5mC, 5-methylcytosine; IQR, interquartile range.

^a N varies obtained based on the success of the pyrosequencing analysis and ELISA.

^bMann–Whitney U test.