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. Author manuscript; available in PMC: 2021 Aug 1.
Published in final edited form as: Anesth Analg. 2020 Aug;131(2):631–639. doi: 10.1213/ANE.0000000000004741

Figure 2. The effect of anesthetics on TLR2 activation in THP-1 cells.

Figure 2.

TLR2 activation by (A) TLR1/TLR2 agonist Pam3CSK4 (100 ng/mL) and (B) TLR2/TLR6 agonist LTA (10 μg/mL) was examined under anesthetics (isoflurane, sevoflurane, dexmedetomidine or propofol) in THP-1 blue cell system. Data were shown as mean +/− S.D. 8 independent replicates were used per group. Statistical analysis was performed using Kruskal-Wallis test with Dunns post hoc analysis. *, ** and *** adjusted p< 0.05, < 0.01, and < 0.001 vs samples stimulated with TLR2 ligands and without anesthetics. n.s = not significant.