The effect of anesthetics (isoflurane, sevoflurane, dexmedetomidine or propofol) on neutrophil L-selectin shedding (A) and CD11b expression (B) was examined. Data were shown as mean +/− S.E. of mean of 6 independent experiments. Statistical analyses were performed using Kruskal-Wallis test with Dunns post hoc analysis. n.s.= not significant. * and ** adjusted p<0.05 and < 0.01 vs TLR2 ligand stimulation groups without anesthetics, respectively. ISO; isoflurane, SEVO; sevoflurane, DEX; dexmedetomidine.