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. Author manuscript; available in PMC: 2021 Apr 10.
Published in final edited form as: J Control Release. 2020 Jan 7;320:45–62. doi: 10.1016/j.jconrel.2020.01.009

Table 1.

Summary of studies using iron oxide nanoparticles for brain tumor applications.

Application Type of study References

Imaging
MRI (Negative contrast) preclinical model [64,192195,203204,206209,209210,213,102103,105,126,174]
MRI (Positive contrast) preclinical model [202,205]
MRI clinical, human patients [211,212]
MPI preclinical model [214]
Targeting
Magnetic targeting preclinical model [8,196199,203204,93,102,89]
Treatment
Delivery of therapeutic molecules preclinical model [199200,206,209210]
Magnetic hyperthermia preclinical model [201]
Magnetic hyperthermia clinical, human patients [215]
Cell based preclinical model [209,208,216]