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. 2020 Nov 2;76(5):492–505. doi: 10.1097/FJC.0000000000000892

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Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 5. — Simplified schematic illustrations of drug-induced alterations of AF-related electrophysiological parameters during AF and the consistency of these alterations with reentrant and focal sources as the underlying mechanisms of AF maintenance. The pattern of the anti-AF agent-induced alterations [ie, prolongation of EG and AFCL, improvement in AF organization (AF-org), etc.] seems to be more consistent with focal source than with reentry as the prime mechanism of AF maintenance. Please see text for details.