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. 2020 Sep 17;127(11):1404–1418. doi: 10.1161/CIRCRESAHA.120.317703

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© 2020 American Heart Association, Inc.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

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Figure 1. — Cytokine and chemokine levels in plasma from patients with coronavirus disease 2019 (COVID-19). Heat map visualization of 48 cytokine/chemokine expression profiles in plasma of patients with COVID-19 nonsevere (median of n=10) and severe (median of n=9) relatively to the healthy controls (median of n=10). Cytokine/chemokine expression is represented as a (log2) fold change relative to healthy controls. The numbers in each part represent the change and statistical significance (in brackets), and the color codes refer to red for increased expression and blue for decreased expression. Absolute cytokine/chemokine values (pg/mL) and details on the statistical analysis are shown in Figure VII in the Data Supplement. *P<0.05, **P<0.01, ***P<0.001, ****P<0.0001.