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. 2020 Oct 26;2020:1346493. doi: 10.1155/2020/1346493

Table 3.

In vitro antisickling activity of plant species used in the management of sickle cell disease in Kikwit.

Plant species Antisickling activity
1 Albizia ferruginea (Guill. et piero) Benth. +
2 Alchornea cordifolia Müll. Arg. +++
3 Alternanthera bettzickiana repens (L.) Link +++
4 Annona senegalensis Pers. +++
5 Bougainvillea sp comm. Ex Juss +
6 Bridelia ferruginea Benth. ++
7 Carica papaya L. ++
8 Ceiba pentandra (L.) Gaertn. +
9 Dissotis brazzae Cogn. +++
10 Ficus asperifolia Müg ++
11 Ficus tremula Warb. ++
12 Gardenia leopoldiana De Wild & T. Durand +
13 Hymenocardia acida Tul ++
14 Hypoxis angustifolia Lam. +++
15 Justicia secunda Vahl +++
16 Leocus africanus (Bak. ex. Elliot) J. K. Morton ++
17 Millettia laurentii De Wild +
18 Morelia senegalensis A. Rich. ex DC ++
19 Rungia grandis T. Ander ++
20 Sterculia bequaertii De Wild ++
21 Stipularia africana P. Beauv. ++
22 Treculia africana Decne ++
23 Vigna unguiculata (L.) Welp +++

+++: ≥80% of normalization rate; ++: 70% of normalization rate; +: 50% of normalization rate. An extract is considered to possess very high activity (+++) if normalization >70%; high activity (++) if 50< normalization <70%; weak activity (+) if 10< normalization <50%; no activity (−) if normalization <10% (14).