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. 2020 Jun 15;48(14):e82. doi: 10.1093/nar/gkaa484

Table 2.

Result of the performance comparison for the identification of high binding-affinity aptamers

Methods Data1_4R TPR Data2_6R TPR
RaptRanker 0.524 0.361
Enrichment 0.238 0.333
Frequency 0.143 0.194
MPBind 0.000 0.250

We compared the performance of high binding-affinity aptamers identifying on two HT-SELEX datasets. The evaluation metrics is ‘True Positive Rate (TPR) when False Positive Rate (FPR) is 0’. We compared at 4R and 6R, the last round of inputs for each dataset. For each dataset, the highest values are shown in bold.