Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jun 25;48(14):7748–7766. doi: 10.1093/nar/gkaa529

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 2. — Epigenetic state of heterochromatin in mESCs and H3K27me3 dynamics during mouse blastocyst development. (A, B) ICC of H3K27me3 (green) and H2AK119Ubiquitin (green) in indicated cells with DAPI (blue) and merge (turquoise represents overlapping signal). White outlined nuclei are ‘zoomed in’ images of representative nuclei. Numbers represent the percentage of cells where green foci overlap with DAPI stained heterochromatin. Scale bar 50 μm. (C) ICC for H3K27me3 (green) with DAPI (pseudocoloured red). Whole and part embryo confocal projections and highlighted cells from the inner ICM and the ICM margin (yellow represents overlapping signal), as indicated; scale bars 10 μm. Arrowheads indicate three cells showing heterochromatic H3K27me3 staining.